Endocrine Abstracts

Objective: Growth hormone (GH) is used for metabolic indications in the treatment of adult patients with GH deficiency (GHD). In addition to influencing growth processes in childhood, GH is important in regulating metabolic processes at every stage of life. GH, via insulin-like growth factor (IGF-1), has an anabolic effect on protein metabolism, also in skeletal muscles and cardiac muscle. Moreover, myokines produced by muscle fibers stimulated by muscle contraction, acting in...